SubtiBank SubtiBank
Version comparison:

2017-07-30 17:44:50Tue Dec 13 2016 11:16:30 GMT+0100 (CET)

proteinLength

363

geneLength

1089

Gene

Coordinates

102,484 → 103,575

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-B930 (yacI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1929 NBRP B. subtilis, Japan]

''mcsB::aphA3'' availbale from the Gerth lab

mcsBC167S::spec available from the Gerth lab

GP1457 (''mcsB''::''aphA3''), available in [SW|Jörg Stülke]'s lab

BP69 (spc), available in [SW|Fabian Commichau]'s lab

''mcsB::aphA3'' availbale from the Gerth lab

mcsBC167S::spec available from the Gerth lab

GP1457 (''mcsB''::''aphA3''), available in [SW|Jörg Stülke]'s lab

BP69 (spc), available in [SW|Fabian Commichau]'s lab

aminos

MSLKHFIQDALSSWMKQKGPESDIVLSSRIRLARNFEHIRFPTRYSNEEASSIIQQFEDQFSEQEIPGIGKFVLIRMNDAQPLEKRVLVEKHLISPNLTESPFGGCLLSENEEVSVMLNEEDHIRIQCLFPGFQLLEAMKAANQVDDWIEEKVDYAFNEQRGYLTSCPTNVGTGLRASVMMHLPALVLTRQINRIIPAINQLGLVVRGIYGEGSEAVGNIFQISNQITLGKSEQDIVEDLNSVAAQLIEQERSAREAIYQTSKIELEDRVYRSYGVLSNCRMIESKETAKCLSDVRLGIDLGIIKGLSSNILNELMILTQPGFLQQYSGGALRPNERDIRRAALIRERLHLEMNGKRQEDESI

[SW|Categories] containing this gene/protein

[SW|protein modification], [SW|transcription factors and their control], [SW|sporulation proteins], [SW|general stress proteins (controlled by SigB)], [SW|heat shock proteins]

Gene

Coordinates on the chromosome (coding sequence)

102,484 -> 103,575

The protein

[SW|Interactions]

[[protein|McsA]]-[[protein|McsB]]-[[protein|CtsR]], [[protein|McsB]]-[[protein|CtsR]] [Pubmed|20852588], [[protein|McsA]]-[[protein|McsB]]

[[protein|McsB]]-[[protein|YwlE]] [Pubmed|20852588]

[[protein|McsB]]-[[protein|ClpP]]/[[protein|ClpC]] (rapid degradation of phosphorylated McsB) [Pubmed|20852588]

Expression and Regulation

Operon

''[[protein|ctsR]]-[[protein|mcsA]]-[[protein|mcsB]]-[[protein|clpC]]-[[protein|radA]]-[[protein|disA]]'' [Pubmed|8793870]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|8793870], [[protein|SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/8793870 PubMed1] [http://www.ncbi.nlm.nih.gov/pubmed/11544224 PubMed2], [[protein|SigF]] [Pubmed|16497325]

Expression and Regulation

Regulation

expressed early during sporulation in the forespore ([[protein|SigF]]) [Pubmed|16497325]

induced by stress ([[protein|SigB]]) [Pubmed|11544224]

induced by heat ([[protein|CtsR]]) [Pubmed|9987115]

Expression and Regulation

Regulatory mechanism

[[protein|CtsR]]: transcription repression [Pubmed|9987115]